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Total 25327 results found since Jan 2013.

Effects of Gentiana lutea root on vascular diseases.
CONCLUSION: Gentiana species and their constituents affect many different factors related to vascular disease development and progression. Therefore, Gentiana-based therapeutics represent potentially useful drugs for the management of vascular diseases. PMID: 32469702 [PubMed - as supplied by publisher]
Source: Current Vascular Pharmacology - May 28, 2020 Category: Drugs & Pharmacology Authors: Joksic G, Radak D, Sudar-Milovanovic E, Obradovic M, Radovanovic J, Isenovic ER Tags: Curr Vasc Pharmacol Source Type: research

A comprehensive approach to complementary and alternative medicine usage among patients from a vascular department
CONCLUSIONS: CAM use is frequent and perceived as safe and beneficial among VS outpatients; nonetheless, patients do not disclose CAM use with their primary vascular surgeons, and a wide range of reasons are given by the patients that prevent effective and open communication.PMID:33853457 | DOI:10.1177/17085381211006595
Source: Vascular - April 15, 2021 Category: Surgery Authors: Cesar Cuen-Ojeda Carlos A Hinojosa Iraz ú Contreras-Yáñez Erika Elenes-S ánchez Casandra Rosas-R íos Miguel A M éndez-Sosa Angel Ballinas-S ánchez Virginia Pascual-Ramos Source Type: research

Rhizoma Coptidis for Alzheimer's Disease and Vascular Dementia: A Literature Review.
Abstract BACKGROUND: Alzheimer's disease (AD) and vascular dementia (VaD) are major types of dementia, which both cause heavy economic burdens for families and society. However, no currently available medicines can control dementia progression. Rhizoma Coptidis, a Chinese herbal medicine, has been used for >2000 years, and is now gaining attention as a potential treatment for AD and VaD. METHODS: We reviewed the mechanisms of the active ingredients of Rhizoma Coptidis and Rhizoma Coptidis-containing Chinese herbal compounds in the treatment of AD and VaD. We focused on studies on ameliorating the risk fact...
Source: Current Vascular Pharmacology - July 9, 2019 Category: Drugs & Pharmacology Authors: Wang Z, Yang Y, Liu M, Wei Y, Liu J, Pei H, Li H Tags: Curr Vasc Pharmacol Source Type: research

Editorial: Vascular Protection of Herbal Medicine: Roles and Mechanisms.
PMID: 29022508 [PubMed - in process]
Source: Current Vascular Pharmacology - October 13, 2017 Category: Drugs & Pharmacology Authors: Liu Y, Liu Y Tags: Curr Vasc Pharmacol Source Type: research

Activation of Nrf2/HO-1 signaling: An important molecular mechanism of herbal medicine in the treatment of atherosclerosis via the protection of vascular endothelial cells from oxidative stress
CONCLUSION: Our present paper provides updated information of natural agents with protective activities on ECs against oxidative stress by activating Nrf2/HO-1. We hope this review will provide some directions for the further development of novel candidate drugs from natural agents for the treatment of AS and other CVDs.PMID:35024180 | PMC:PMC8655139 | DOI:10.1016/j.jare.2021.06.023
Source: Atherosclerosis - January 13, 2022 Category: Cardiology Authors: Qing Zhang Jia Liu Huxinyue Duan Ruolan Li Wei Peng Chunjie Wu Source Type: research

Baicalin, baicalein and wogonin inhibits high glucose-induced vascular inflammation in vitro and in vivo.
Abstract Vascular inflammatory process has been suggested to play a key role in initiation and progression of atherosclerosis, a major complication of diabetes mellitus. Thus, in this study, we attempted to determine whether three structurally related polyphenols found in the Chinese herb Huang Qui, namely baicalin, baicalein, and wogonin, can suppress vascular inflammatory processes induced by high glucose (HG) in human umbilical vein endothelial cells (HUVECs) and mice. Data showed that HG induced markedly increased vascular permeability, monocyte adhesion, expressions of cell adhesion molecules (CAMs), formatio...
Source: BMB Reports - March 5, 2015 Category: Biochemistry Authors: Ku SK, Bae JS Tags: BMB Rep Source Type: research

The effect of Chinese herbal medicine combined with western medicine on vascular endothelial function for patients with hypertension: Protocol for a systematic review and meta-analysis
Conclusion: This systematic review will determine whether TCM combined with western medicine provides evidence for effective intervention of vascular endothelial function in patients with essential hypertension. Ethics and dissemination: This systematic review and meta-analysis of randomized controlled trials does not require ethical recognition, and the results of this paper will be published in an open access, internationally influential academic journal. PROSPERO registration number: CRD42019140743
Source: Medicine - December 1, 2019 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research

Padma 28 for intermittent claudication.
CONCLUSIONS: Some evidence exists from individual trials to suggest that Padma 28 may be effective in increasing walking distances, at least in the short term (four months), in people with IC. Side effects do not appear to be a problem. However, the longer term effects of treatment are unknown and the clinical significance of the improvements in walking distance are questionable. Moreover, the quality of the evidence is limited by the small sample size of the available trials, limited reporting of statistical analyses that compared treatment groups, and relatively high withdrawal rates that were linked to the outcome. That...
Source: Cochrane Database of Systematic Reviews - March 28, 2016 Category: Journals (General) Authors: Stewart M, Morling JR, Maxwell H Tags: Cochrane Database Syst Rev Source Type: research

Traditional Chinese herbal medicine for vascular dementia.
CONCLUSIONS: We found moderate- to very low-quality evidence of benefit and harm of TCHMs for VaD. Methodological inadequacies need to be addressed by better conducted and reported trials. We identified NaoMaiTai, NaoXinTong and TongXinLuo as warranting special research priority. PMID: 30520514 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - December 6, 2018 Category: General Medicine Authors: Chan ES, Bautista DT, Zhu Y, You Y, Long JT, Li W, Chen C Tags: Cochrane Database Syst Rev Source Type: research

Vascular Protective Effect and Its Possible Mechanism of Action on Selected Active Phytocompounds: A Review
Evid Based Complement Alternat Med. 2022 Apr 16;2022:3311228. doi: 10.1155/2022/3311228. eCollection 2022.ABSTRACTVascular endothelial dysfunction is characterized by an imbalance of vasodilation and vasoconstriction, deficiency of nitric oxide (NO) bioavailability and elevated reactive oxygen species (ROS), and proinflammatory factors. This dysfunction is a key to the early pathological development of major cardiovascular diseases including hypertension, atherosclerosis, and diabetes. Therefore, modulation of the vascular endothelium is considered an important therapeutic strategy to maintain the health of the cardiovascu...
Source: Atherosclerosis - April 26, 2022 Category: Cardiology Authors: Nur Aqilah Kamaruddin Muhammad Nazrul Hakim Abdullah Jun Jie Tan Vuanghao Lim Lai Yen Fong Siti Aisyah Abd Ghafar Yoke Keong Yong Source Type: research

Chinese herbal medicine for vascular cognitive impairment in cerebral small vessel disease: A protocol for systematic review and meta-analysis of randomized controlled trials
Conclusion: The conclusion about the clinical efficacy and safety of CHM for CSVD-VCI will be provided for clinical plans, decisions, and policy developments in the full version of this systematic review. Systematic review registration: INPLASY202080120.
Source: Medicine - October 2, 2020 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research

Xiaoxuming Decoction Regulates Vascular Function by Modulating G Protein-Coupled Receptors: A Molecular Docking Study
In this study, XXMD was found to induce relaxation of the basilar artery rings of rats precontracted by 5-hydroxytryptamine (5-HT) in vitro, in a dose-dependent manner. The modulation of vascular tone and the process of cerebral ischemia are mediated via the interactions between G protein-coupled receptors (GPCRs) and their ligands, including 5-HT, angiotensin II (Ang II), and urotensin II (UII). Thus, the potential synergistic effects of the different components of XXMD on the regulation of vasoconstriction and vasodilation were further investigated by molecular docking based on network pharmacology. We constructed and an...
Source: Biomed Res - July 1, 2021 Category: Research Authors: Yanjia Shen Ran Yang Rui Zhou Wendan Lu Li Li Ziran Niu Miao Chen Jinhua Wang Yuehua Wang Lianhua Fang Guanhua Du Source Type: research

New insights into vascular aging: Emerging role of mitochondria function
Biomed Pharmacother. 2022 Dec;156:113954. doi: 10.1016/j.biopha.2022.113954. Epub 2022 Nov 8.ABSTRACTVascular aging, a major risk factor for cardiovascular disease, contributes to morbidity and mortality in older people. Mitochondria play an important role in vascular aging. In endothelial and smooth muscle cells, multiple changes in the mitochondrial structure and function contribute to aging, including the effects of mitochondrial oxidative stress, mitochondrial DNA mutations, mitochondrial dynamics, and mitophagy. Mitochondrial dysfunction also contributes to other age-related molecular and cellular mechanisms, such as ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - November 22, 2022 Category: Drugs & Pharmacology Authors: Yu-Juan Li Xiao Jin Dan Li Jing Lu Xiao-Nan Zhang Sheng-Jie Yang Yi-Xi Zhao Min Wu Source Type: research